{"id":10216,"date":"2026-02-16T16:49:51","date_gmt":"2026-02-16T15:49:51","guid":{"rendered":"https:\/\/www.msd.ch\/en\/?page_id=10216"},"modified":"2026-02-16T16:49:52","modified_gmt":"2026-02-16T15:49:52","slug":"enflonsia-publication-of-clinical-trial-results","status":"publish","type":"page","link":"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/","title":{"rendered":"ENFLONSIA\u00ae &#8211; Publication of clinical trial results"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">Publication of clinical trial results<\/h1>\n\n\n\n<p>The information given below and the relevant links to the clinical data fulfil the requirements of Articles 71-73 of the Ordinance on Therapeutic Products (Therapeutic Products Ordinance, TPO). They supplement the information published in association with the Swiss Marketing Authorisation for the medicinal product.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">ENFLONSIA\u00ae<\/h2>\n\n\n\n<p>ENFLONSIA<sup>\u00ae <\/sup>(clesrovimab), solution for intramuscular injection in pre-filled syringe.<br>Each pre-filled syringe contains 105 mg of clesrovimab in 0.7 mL.<\/p>\n\n\n\n<p>Authorisation number: 70145 (Swissmedic)<\/p>\n\n\n\n<p>Date of Marketing Authorisation: 22-Jan-2026<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><br>Clinical Studies<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Protocol MK-1654-004<\/h3>\n\n\n\n<p><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04767373\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Study Details | NCT04767373 | Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004) | ClinicalTrials.gov<\/a><br>NCT04767373<\/p>\n\n\n\n<p><strong>Publication:<\/strong><br>Zar HJ, Sim\u00f5es EAF, Madhi SA, Ramilo O, Senders SD, Shepard JS, Laoprasopwattana K, Piedrahita J, Novoa JM, Vargas SL, Dionne M, Jackowska T, Liu E, Ishihara Y, Ikeda K, Zhang Y, Railkar RA, Lutkiewicz J, Vora KA, Zang X, Maas BM, Lee AW, Guerra A, Sinha A; CLEVER (MK-1654-004) Study Group. Clesrovimab for Prevention of RSV Disease in Healthy Infants. N Engl J Med.&nbsp;2025 Oct 2;393(13):1292-1303.&nbsp;doi: 10.1056\/NEJMoa2502984.&nbsp;Epub 2025 Sep 17.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Protocol MK-1654-007<\/h3>\n\n\n\n<p><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04938830\" target=\"_blank\" rel=\"noreferrer noopener nofollow\"><\/a><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04938830\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Study Details | NCT04938830 | Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007) | ClinicalTrials.gov<\/a><br>NCT04767373<\/p>\n\n\n\n<p><strong>Publication:<\/strong><br>Zar HJ, Bont LJ, Manzoni P, Mu\u00f1oz FM, Ramilo O, Chen PY, Novoa JM, Ordo\u00f1ez GA, Tsolia M, Tapi\u00e9ro B, Acu\u00f1a-\u00c1vila MI, Castellanos JM, Meyer M, Morioka I, Chen Z, Railkar RA, Zang X, Maas BM, Likos A, Lee AW, Castagnini LA, Sinha A; SMART (MK-1654-007) Study Group. Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease. N Engl J Med. 2025 Oct 2;393(13):1343-1345. doi: 10.1056\/NEJMc2506107. Epub 2025 Sep 17.<\/p>\n\n\n\n<p><sup>CH-RSM-00018, 02\/2026<\/sup><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Publication of clinical trial results The information given below and the relevant links to the clinical data fulfil the requirements of Articles 71-73 of the Ordinance on Therapeutic Products (Therapeutic Products Ordinance, TPO). They supplement the information published in association with the Swiss Marketing Authorisation for the medicinal product. ENFLONSIA\u00ae ENFLONSIA\u00ae (clesrovimab), solution for intramuscular [&hellip;]<\/p>\n","protected":false},"author":974,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"editor_notices":[],"footnotes":""},"class_list":["post-10216","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ENFLONSIA\u00ae - Publication of clinical trial results - msd.ch<\/title>\n<meta name=\"description\" content=\"Publication of clinical trial results of ENFLONSIA\u00ae (clesrovimab), which has been authorised by Swissmedic on January 22, 2026.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ENFLONSIA\u00ae - Publication of clinical trial results - msd.ch\" \/>\n<meta property=\"og:description\" content=\"Publication of clinical trial results of ENFLONSIA\u00ae (clesrovimab), which has been authorised by Swissmedic on January 22, 2026.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/\" \/>\n<meta property=\"og:site_name\" content=\"msd.ch\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-16T15:49:52+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/\",\"url\":\"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/\",\"name\":\"ENFLONSIA\u00ae - Publication of clinical trial results - msd.ch\",\"isPartOf\":{\"@id\":\"https:\/\/www.msd.ch\/en\/#website\"},\"datePublished\":\"2026-02-16T15:49:51+00:00\",\"dateModified\":\"2026-02-16T15:49:52+00:00\",\"description\":\"Publication of clinical trial results of ENFLONSIA\u00ae (clesrovimab), which has been authorised by Swissmedic on January 22, 2026.\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.msd.ch\/en\/enflonsia-publication-of-clinical-trial-results\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.msd.ch\/en\/#website\",\"url\":\"https:\/\/www.msd.ch\/en\/\",\"name\":\"msd.ch\",\"description\":\"MSD researches and develops medicines and vaccines to save lives and improve patients&#039; health. 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